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The advantages and characteristics of the freeze dryer are many. First, it is suitable for heat sensitive substances. Since freeze-drying is carried out at low temperatures, it is particularly suitable for many heat-sensitive substances without denaturation or loss of biological activity. Therefore, freeze dryers have been widely used in the food and pharmaceutical industries.
Second, the material loss is small. When drying at low temperatures, some of the volatile components in the material are lost, which is suitable for the drying of some chemical products, medicines and foods.
Third, maintain the shape of the material. In the process of freeze-drying, the growth of microorganisms and the action of enzymes cannot be carried out, the volume is almost constant, the original structure is maintained, concentration phenomenon does not occur, and oxygen is also extremely rare. Therefore, the lyophilizer maintains its original character, does not oxidize, and does not change the material structure.
Fourth, the substance is easily dissolved. The dried material is porous and spongy. After adding water, it dissolves quickly and completely, and returns to the original trait almost immediately.
Fifth, the substance is preserved for a long time. Drying can eliminate more than 95-99% of water, so that the dried product can be preserved for a long time without deterioration. Therefore, freeze drying is currently widely used in the pharmaceutical industry, food industry, scientific research and other sectors.
A number of features and advantages, as well as continued improvement in pharmaceutical demand, have helped to expand the market for freeze dryers. The author understands that in the context of the market's high development, the industry predicts that in 2021, the global freeze dryer market will reach 788 million US dollars, with a compound growth rate of 7.5% in 2016-2021.
In order to better occupy the market, medical equipment companies adhere to the concept of reform and innovation, introduce advanced foreign technology and re-innovation, closely follow FDA, EU, cGMP and other regulations and policies, and develop a risk-based control concept with green energy conservation as the theme. A new high-efficiency freeze dryer to promote and improve the industry standard and quality development of domestic freeze dryers.
Some enterprises have also solved the aseptic control risks of freeze-drying machine sealing, vacuum, silicone oil leakage, CIP cleaning, aseptic assembly and deflation system through the optimization and innovation of the details of each subsystem of the freeze dryer.
In addition, the company actively responds to national policies and cooperates with research institutes of higher research institutes to vigorously support industrial energy conservation, reduce costs and increase efficiency, and develop low-energy refrigeration systems and cabinet structures.
“The lyophilizer developed by us has small volume and high energy efficiency, and realizes the green development of freeze-drying technology. In the future, we will strive to make green environmental protection one of the development directions of the future freeze dryer.†The person in charge of the freeze dryer company said.
Some enterprises have developed a intelligent factory control system with the lyophilizer as the core, providing customers with a complete set of freeze-drying solutions for the production of pharmaceutical preparations and APIs, and combining the energy solutions of pharmaceutical plants to meet customer needs in many aspects.
Driven by policies and market demand, at present, the gap between domestic freeze dryers and foreign advanced freeze dryers is shrinking. Some companies independently develop freeze dryers that not only have high product quality, but also receive key laboratories from various regions. It is favored by researchers in the scientific research, pharmaceutical and food industries.
According to industry insiders, the future development of China's freeze dryer market is optimistic. In order to seize the opportunity, relevant enterprises should understand the development process of equipment and technology from the perspectives of production, technology, quality and verification. This promotes the innovation and healthy development of the freeze-drying industry such as food and medicine.
The freeze dryer is referred to as the "freeze dryer". Under the high vacuum state, the sublimation principle is used to make the moisture in the pre-frozen material not be melted by ice, and directly removed into the water vapor as ice, thereby achieving freeze-drying. purpose.